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A Case Study Analysis: Challenges in the NICE Evaluation of Multi-Indication Medicines for Rare and Ultra-Rare Diseases

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The Oxford Biomedical Research Centre (BRC) was established in April 2007. OHE and RAND Europe were commissioned by the Oxford BRC to undertake a programme of top-down evaluations of aspects of the impact of the BRC since its inception.
The Oxford Biomedical Research Centre (BRC) was established in April 2007. OHE and RAND Europe were commissioned by the Oxford BRC to undertake a programme of top-down evaluations of aspects of the impact of the BRC since its inception.
This programme of research has looked at the health, economic and scientific impact of Oxford BRC’s research activity, whether achieved directly from the outcomes of the many specific pieces of BRC-supported research, or indirectly due to the BRC’s impact on research activity/awareness/culture in health services and industry.
Overall this programme of research indicated that the Oxford BRC has had a number of positive impacts on health care provided at OUH, through both direct and indirect effects. It is clear that Oxford BRC research plays a major role within the totality of research activity at OUH. In particular, Oxford BRC has:
Please note a chapter of this report has also been published in Health Research Policy and Systems.
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