OHE at HTAi Oslo: A New Drug Development Paradigm, a Framework for Developing Formularies in MICs, and the Effect of NICE Decisions Abroad

This post summarises OHE’s activities at the upcoming HTAi meeting in Oslo, June 2015. Topics include the effect of NICE decisions abroad, a framework for developing formularies in MICs, a new drug development paradigm, and a comparison of EQ-5D-5L and EQ-5D-3L.

HTAi’s 12th Annual Meeting, Global Efforts in Knowledge Transfer: HTA to Health Policy and Practice, is scheduled for 15-17 June 2015 in Oslo. Members of the OHE team will be attending and presenting key research. Scheduled presentations are summarised below.

New Clinical Development Paradigm for Drugs

Sean Tunis (Center for Medical Technology Policy: CMTP), Adrian Towse (OHE), Sarah Garner (NICE Franz Pichler (Eli Lilly).

This workshop combines knowledge from two projects: (i) the New Drug Development Project, undertaken by CMTP and OHE, funded by five companies, which set out development pathways for different drug ‘archetypes’ and (ii) initial findings from the Innovative Medicines Initiative (IMI) ‘GetReal’ Project proposing innovative (more pragmatic) trial designs in pre-and post-launch drug development. The target audience includes drug developers, clinical trial reviewers and methodologists, HTA evidence assessors, HTA decision makers. The objective is to share knowledge about the likely changes in the type of evidence that is generated in the drug development process and the impact that HTA bodies can have on that process.

Sunday 14 June, 1:30 PM
Workshop ID: 14

A Decision Making Framework for Developing Formularies in Middle Income Countries

Karla Hernández-Villafuerte (OHE), Martina Garau (OHE), Adrian Towse (OHE), Lou Garrison (University of Washington), Simrun Grewal (University of Washington), David Grainger (Eli Lilly).

This presentation outlines the methodology and preliminary findings of our work to develop recommendations on the methods and processes for identifying medicines for national formularies in middle income countries (MICs). It explores potential links between “macro-level” decision-making (approaches to designing and organizing the health system) and “micro-level” decision-making (related to decisions on individual health technologies).

Preliminary findings show that the existing literature explores issues related to health systems strengthening and decision making on coverage of individual health technologies separately. Approaches to formulary decisions need to explore how to combine treatment-specific factors (e.g., clinical effectiveness), with factors related to health system design (e.g., disease priorities) and financing (including affordability).